Basic Science

The basic knowledge for reappropriating trans medicine

The six pages of this section are aimed at giving you general information on hormones - and more specifically sex hormones - and other biological functions involved in transgender Hormone Replacement Therapy (HRT). If you don’t know much about this, we recommend reading them in the proposed order, since they’ll build on each other.


What are steroid hormones?

What are hormones, and what are steroid hormones?

Sex Hormones: how do they work?

About estrogens, androgens and progestogens: how hormones work, applied to sex hormones.

The different estrogens, androgens and progestogens, and their binding affinity

More detail about the three groups of sex hormones, and why knowing about them is important

The self-regulation mechanism, and how to use it in our benefits

About the negative feedback mechanism, the centerpiece of HRT

Growth hormones

About growth hormones, why it can be important to think about it, and why you should not just “take some”.

DHEA and intracrinology

On the adrenal hormone DHEA, why it matters, and if tranfem people should stop taking blockers after SRS.

Last modified May 31, 2023: Content update (fb1474c)